Xepi

Xepi is a prescription medication used to treat impetigo, a bacterial skin infection.

Xepi belongs to a group of drugs called fluoroquinolone antibiotics. These work by killing the bacteria.

This medication comes in topical form and is applied 2 times a day.

Side effects may include red skin and scaly patches.

Xepi is a prescription medication approved for the topical treatment of impetigo due to Staphylococcus aureus or Streptococcus pyogenes in adult and pediatric patients 2 months of age and older.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Apply a thin layer of Xepi topically to the affected area twice daily for 5 days.

Serious side effects have been reported with Xepi including the following:

• the potential for bacteria overgrowth. If Xepi is used for an extended period of time, bacteria that Xepi does not kill and fungi can overgrow.

Side effects of Xepi that have been reported include:

• rosacea, a skin condition redness and other skin symptoms typically on the face.
• seborrheic dermatitis, a skin condition with scaly patches.

This is not a complete list of Xepi side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effects that bother you or that do not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

No drug interactions have been determined by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Tell your doctor if you are pregnant or plan to become pregnant.

There are no well-done studies that have been done in humans with Xepi. In animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Since Xepi is only for topical use, the amount of Xepi absorbed into the system is negligible. When pregnant women use Xepi, It is not expected that fetal exposure will occur.

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Xepi crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Xepi.

Since Xepi is only for topical use, the amount of Xepi absorbed into the system is negligible. When breastfeeding women use Xepi, It is not expected that baby exposure will occur.