Medication

Rocephin

Generic name: ceftriaxone

Pharmacist-reviewed drug information from the RxWiki encyclopedia.

Overview

Rocephin is a prescription medication used to treat bacterial infections such as gonorrhea, pelvic inflammatory disease, and infections of the brain, spinal cord, lungs, ears, skin, urinary tract, blood, bones, joints, and stomach. Rocephin belongs to a group of drugs called cephalosporin antibiotics, which work to stop the growth of bacteria in the body.

This medication is available in an injectable form to be given directly into a vein (IV) or muscle (IM) by a healthcare professional.

Common side effects of Rocephin include irritation at the site of injection, rash, and diarrhea.

What is it used for?

Rocephin is a prescription medication used to treat bacterial infections such as gonorrhea, pelvic inflammatory disease, and infections of the brain, spinal cord, lungs, ears, skin, urinary tract, blood, bones, joints, and stomach.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

How to take it

Take Rocephin exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Rocephin dose your doctor recommends will be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your kidney and liver function
  • your weight
  • your age

The recommended dose range for Rocephin in children is 50 mg/kg to 4 grams total once a day or divided into even doses given twice a day.

The recommended dose range for Rocephin  in adults is 250 mg to 4 grams total once a day or divided into even doses given twice a day.

Warnings

Serious side effects have been reported with Rocephin including:

  • hypersensitivity (severe allergic reaction). Signs of a hypersensitivity reaction, which include the following:
    • chest pain
    • swelling of the face, eyes, lips, tongue, arms, or legs
    • difficulty breathing or swallowing
    • fainting
    • rash
  • diarrhea. Diarrhea is a common problem caused by antibiotics, and it usually ends when the antibacterial is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as 2 or more months after having taken their last dose of the antibacterial. If diarrhea is severe or lasts more than 2 or 3 days, contact your doctor, as this may be a sign of an infection of the bowels.
  • superinfection. Rocephin should not be used for extended periods. Prolonged use can lead to the growth of dangerous organisms that are resistant or unresponsive to this medication. Take Rocephin for the duration prescribed by your doctor.
  • bleeding abnormalities. Your health care provider may want to monitor lab tests that show how well your blood is able to clot or that measure your tendency to bleed. Any abnormalities or irregularities that may occur may be more common in those with kidney dysfunction.
  • nervous system disturbances. Some may experience nervous symptom abnormalities such as a seizure or disturbances of consciousness (confusion, hallucinations, stupor, coma) when the dose of Rocephin exceeds the recommended dose, especially in the presence of kidney dysfunction.

Do not take Rocephin in the following situations:

  • in those who are allergic to Rocephin or to any of its ingredients
  • in hyperbilirubinemic neonates, especially premature infants
  • in neonates if they require (or are expected to require) treatment with calcium-containing IV solutions, including continuous calcium-containing infusions such as parenteral nutrition

Side effects

Common side effects of Rocephin include:

  • irritation at the site of injection
  • diarrhea
  • rash
  • nausea
  • vomiting
  • altered taste

This is not a complete list of Rocephin side effects. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Rocephin. See the “Drug Precautions” section.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Drug interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • probenecid (Probalan, Benemid)
  • methotrexate (Trexall, Rheumatrex)
  • birth control pills

This is not a complete list of Rocephin drug interactions. Ask your doctor or pharmacist for more information.

Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Rocephin falls into category B. There are no well-done studies that have been done in humans with Rocephin. But in animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Breastfeeding

Tell your doctor if you are breastfeeding or plan to breastfeed.

Rocephin has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from Rocephin , a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.

Quick facts

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take birth control pills.

Diarrhea is a common problem caused by antibiotics, and it usually ends when the antibacterial is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) If diarrhea is severe or lasts more than 2 or 3 days, contact your doctor, as this may be a sign of an infection of the bowels.

Before taking Rocephin, tell your doctor about all of your medical conditions. Especially tell your doctor if you are allergic to similar antibiotics (penicillins).

All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.