Mevacor

Mevacor is a prescription medication used to treat high cholesterol levels and to prevent heart disease. Mevacor belongs to a group of drugs called HMG-CoA reductase inhibitors, also known as statins. It works by decreasing the amount of cholesterol made in the body.

This medication comes as a tablet and is taken once or twice a day with meals.

Common side effects include constipation, memory loss, confusion, and and dizziness or blurred vision. Do not drive or operate heavy machinery until you know how Mevacor affects you.

Mevacor is a prescription medication used to treat high cholesterol levels.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

• the condition being treated
• other medical conditions you have
• other medications you are taking
• how you respond to this medication
• your weight
• your height
• your age
• your gender

The recommended dosing range of Mevacor is 10 to 80 mg/day in single or two divided doses. The maximum recommended dose is 80 mg/day. 

Serious side effects have been reported with Mevacor including:

• Myopathy and rhabdomyolysis (muscle damage and dysfunction): Tell your healthcare provider right away if you have some or all of the following symptoms:
  • muscle pain
  • muscle tenderness
  • muscle weakness. Mevacor therapy should be discontinued immediately if myopathy is diagnosed or suspected.
• Liver problems: Tell your healthcare provider right away if you have some or all of the following symptoms of liver problems:
  • feeling tired or weak
  • loss of appetite
  • upper belly pain
  • dark, amber colored urine
  • yellow tinting of the skin or eyes
• Homozygous Familial Hypercholesterolemia: Use of Mevacor for this rare genetic disorder (increased cholesterol levels) is not sufficient enough for treatment. More aggressive therapies are typically required.

Mevacor can cause dizziness or blurred vision. Do not drive or operate heavy machinery until you know how Mevacor affects you.

Do not take Mevacor if you:

• take medications that stop the function of the CYP3A4 enzyme (e.g. itraconazole, ketoconazole, posaconazole, voriconazole, clarithromycin, telithromycin, HIV protease inhibitors, boceprevir, telaprevir, and nefazodone)
• use erythromycin
• are allergic to Mevacor or any ingredient found in this medication
• active liver disease, which may include unexplained high levels of markers of liver function
• are pregnant or are breast feeding

Serious side effects have been reported with Mevacor. See "Drug Precautions" section.

Common side effects of Mevacor include:

• constipation
• memory loss or forgetfulness
• confusion
• muscle pain, tenderness, or weakness
• fever
• nausea
• blurred vision
• itching
• rash

This is not a complete list of Mevacor side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• amiodarone (Cordarone, Pacerone)
• cimetidine (Tagamet)
• clarithromycin (Biaxin)
• colchicine (Colcrys)
• danazol (Danocrine)
• cyclosporine (Neoral, Sandimmune)
• spironolactone (Aldactone)
• erythromycin (E.E.S., E-Mycin, Erythrocin)
• oral contraceptives (birth control pills)
• spironolactone (Aldactone)
• telithromycin (Ketek)
• verapamil (Calan, Covera, Isoptin)
• warfarin (Coumadin, Jantoven)
• antifungal medications such as itraconazole (Sporanox), posaconazole (Noxafil), and ketoconazole (Nizoral)
• HIV protease inhibitors such as amprenavir (Agenerase), atazanavir (Reyataz), and darunavir (Prezista)
• other cholesterol-lowering medications such as fenofibrate (Tricor), gemfibrozil (Lopid), and niacin (nicotinic acid, Niacor, Niaspan)

This is not a complete list of Mevacor side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Mevacor falls into category X. This drug should not be used during pregnancy as it has the potential to cause miscarriage or severe birth defects.

Mevacor may harm your unborn baby.

Tell your doctor if you are breastfeeding or plan to breastfeed.

You should not take Mevacor if you are breastfeeding. It may be excreted in your breast milk and may harm your nursing child.

Mevacor can cause myopathy and rhabdomyolysis (muscle damage and dysfunction). Tell your healthcare provider right away if you have some or all of the following symptoms:

• muscle pain
• muscle tenderness
• muscle weakness.

Grapefruit and grapefruit juice may interact with Mevacor and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.

Before taking Mevacor, tell your doctor if you drink alcohol on a daily basis.

Take Mevacor with meals.

Mevacor should not be used during pregnancy.