Medication

Glyset

Generic name:

Pharmacist-reviewed drug information from the RxWiki encyclopedia.

Overview

Glyset is a prescription medication used to treat type 2 diabetes.

Glyset belongs to a group of drugs called alpha-glucosidase inhibitors. These work by slowing the action of certain chemicals that digest sugars, which results in decreased blood sugar after meals.

This medication comes in tablet form and is taken three times a day, with the first bite of each main meal.

Common side effects of Glyset include abdominal pain, diarrhea, and flatulence.

In combination with other medications to treat diabetes, Glyset can also cause hypoglycemia (low blood sugar), which can cause blurred vision and dizziness. Do not drive or operate heavy machinery until you know how Glyset affects you.

What is it used for?

Glyset is a prescription medication used to treat type 2 diabetes along with diet and exercise.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

How to take it

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication

The recommended starting dose of Glyset for the treatment of type 2 diabetes is 25 mg three times daily. Dose increases should be individualized on the basis of effectiveness and tolerance. The maximum recommended dose of Glyset is 100 mg three times daily.

Warnings

Serious side effects have been reported with acarbose including the following:

  • Hypoglycemia. When used in combination with other medications to treat type 2 diabetes, acarbose can cause hypoglycemia (low blood sugar). Tell your healthcare provider right away if you have some or all of the following symptoms of hypoglycemia:
    • shakiness
    • dizziness or lightheadedness
    • sweating
    • nervousness or irritability
    • sudden changes in behavior or mood
    • headache
    • numbness or tingling around the mouth
    • weakness
    • pale skin
    • hunger or thirst
    • clumsy or jerky movements
    • confusion
    • weakness
    • blurred vision

Do not take Glyset if you:

  • are allergic to Glyset or to any of its ingredients
  • have diabetic ketoacidosis
  • have cirrhosis
  • have inflammatory bowel disease, colonic ulceration, or partial intestinal obstruction
  • have chronic intestinal diseases or disorders of digestion or absorption
  • have conditions that may deteriorate as a result of increased gas formation in the intestine

Side effects

Serious side effects have been reported with Glyset. See the "Glyset Precautions" section.

Common side effects of Glyset include:

  • abdominal pain
  • diarrhea
  • gas
  • skin rash

This is not a complete list of Glyset side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Drug interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • other medications for diabetes
  • digestive enzymes (Viokase, Pancrease, or Ultrase)
  • digoxin (Lanoxin)
  • propranolol (Inderal)
  • ranitidine (Zantac)
  • vitamins

This is not a complete list of Glyset drug interactions. Ask your doctor or pharmacist for more information.

Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Glyset falls into category B.

There are no well-done studies that have been done in humans with Glyset. In animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Breastfeeding

Tell your doctor if you are breastfeeding or plan to breastfeed.

Glyset has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from Glyset, it is recommended that Glyset not be administered to nursing women.

All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.