Medication

Endocodone

Generic name: oxycodone

Pharmacist-reviewed drug information from the RxWiki encyclopedia.

Overview

Oxycodone is a prescription medication used to treat moderate to severe pain. This medication belongs to a group of drugs called opioids which work by stopping pain signals made in the brain.

Oxycodone comes in several forms including tablets, capsules, oral solution (liquid) and extended-release tablets. It is also found in combination with other medications such as acetaminophen, ibuprofen, and aspirin.

Common side effects of oxycodone include constipation, nausea, drowsiness, and dizziness. Do not drive or operate heavy machinery until you know how it affects you.

What is it used for?

Oxycodone is a prescription medicine used to treat moderate to severe pain.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

How to take it

Take oxycodone exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. Your doctor will determine the best dose for you. The dosage of oxycodone must be individualized.

Warnings

  • Do not drive, operate heavy machinery, or participate in any other possibly dangerous activities until you know how you react to this medicine. This medication can make you sleepy.
  • Do not drink alcohol while using oxycodone. It may increase the chance of getting dangerous side effects.
  • Do not take other medicines without your doctor’s approval. Other medicines include prescription and non-prescription medicines, vitamins, and supplements. Be especially careful about products that make you sleepy.

Do not take oxycodone if

  • your doctor did not prescribe it for you
  • are allergic to any of its ingredients
  • have had a severe allergic reaction to a medicine that contains oxycodone. Ask your healthcare provider if you are not sure.
  • are having an asthma attack or have severe asthma, trouble breathing, or any lung problems
  • have a bowel blockage called paralytic ileus
  • have recently had a head injury
  • you have a history of drug or alcohol dependence
  • you have had a severe allergic reaction to codeine, hydrocodone, dihydrocodeine, or oxycodone (such as Tylox, Tylenol with Codeine, or Vicodin). A severe allergic reaction includes a severe rash, hives, breathing problems, or dizziness.

Oxycodone can cause serious breathing problems that can become life-threatening, especially if oxycodone is used the wrong way. Call your healthcare provider or get medical help right away if:

  • your breathing slows down
  • you have shallow breathing (little chest movement with breathing)
  • you feel faint, dizzy, confused, or
  • you have any other unusual symptoms

Oxycodone can cause your blood pressure to drop. This can make you feel dizzy and faint if you get up too fast from sitting or lying down. Low blood pressure is also more likely to happen if you take other medicines that can also lower your blood pressure. Severe low blood pressure can happen if you lost blood or take certain other medicines.

There is a chance of abuse or addiction with oxycodone. The chance is higher if you are or have been addicted to or abused other medicines, street drugs, or alcohol, or if you have a history of mental problems.

Side effects

Serious side effects have been reported. See "Drug Precautions" section.

Common side effects include:

  • nausea
  • constipation
  • vomiting
  • headache
  • itching

This is not a complete list of oxycodone side effects. Ask your doctor or pharmacist for more information.

Drug interactions

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Be especially careful about taking other medicines that make you sleepy such as:

  • pain medicines
  • sleeping pills
  • anxiety medicines
  • antihistamines
  • anti-depressants
  • tranquilizers
  • anti-nausea medicine
  • alcohol

This is not a complete list of oxycodone drug interactions. Ask your doctor or pharmacist for more information.

Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Oxycodone falls into category B. There are no well-done studies that have been done in humans with oxycodone. But in animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Breastfeeding

Oxycodone has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from oxycodone, a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.

 

Quick facts

Common side effects of oxycodone include constipation, drowsiness, and dizziness. Do not drive or operate heavy machinery until you know how it affects you.

Oxycodone may cause stomach upset. Taking it with food may help.

Do not drink alcohol while using oxycodone. It may increase the chance of getting dangerous side effects.

Oxycodone can cause serious breathing problems that can become life-threatening, especially if oxycodone is used the wrong way. Call your healthcare provider or get medical help right away if your breathing slows down or if you have shallow breathing (little chest movement with breathing).

If you take more oxycodone than prescribed, or overdose, call your local emergency number (such as 911) or your local Poison Control Center right away, or get emergency help.

All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.