Medication

Cutivate

Generic name: fluticasone

Pharmacist-reviewed drug information from the RxWiki encyclopedia.

Overview

Fluticasone oral inhalation is a prescription medication used to prevent difficulty breathing, chest tightness, wheezing, and coughing caused by asthma. Fluticasone is in a class of medications called corticosteroids. It works by decreasing swelling and irritation in the airways to allow for easier breathing.

Fluticasone nasal spray is a prescription medication to treat the symptoms of allergic and nonallergic rhinitis. Fluticasone is in a class of medications called corticosteroids. It works by preventing and decreasing inflammation (swelling that can cause other symptoms) in the nose.

Fluticasone cream, ointment, and lotion are prescription medications used to reduce inflammation and relieve itching, redness, dryness, and scaling associated with various skin conditions. Fluticasone is in a class of medications called corticosteroids. It works by decreasing inflammation involved with skin diseases.

Fluticasone oral inhalation is typically used twice daily. The nasal spray is sprayed into each nostril once or twice daily. The cream and lotion forms are applied to the affected area typically once or twice a day.

Common side effects of fluticasone inhalational include upper airway infection or inflammation, throat irritation, and cough.

Common side effects of fluticasone nasal spray include cough, nosebleeds, and nasal burning or irritation.

Common side effects of fluticasone topical include irritation at site of application.

What is it used for?

Inhalational:

  • Fluticasone oral inhalation is a prescription medication used to prevent difficulty breathing, chest tightness, wheezing, and coughing caused by asthma.

Topical:

  • Fluticasone nasal spray is a prescription medication used to treat symptoms of nasal inflammation, known medically as rhinitis, that may or may not be associated with allergies. Symptoms treated include:
    • sneezing
    • runny, stuffy, and itchy nose
  • Fluticasone cream, ointment, and lotion are prescription medications used to reduce inflammation and relieve itching, redness, dryness, and scaling associated with various skin conditions.
  • This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Warnings

Inhalational:

  • fungal infections (thrush) in your mouth and throat. Tell your doctor if you have any redness or white-colored coating in your mouth
  • decreased adrenal function (adrenal insufficiency). Symptoms of decreased adrenal function include tiredness, weakness, nausea and vomiting, and low blood pressure. Decreased adrenal function can lead to death.
  • allergic reaction (anaphylaxis). Call your doctor and stop fluticasone right away if you have any symptoms of an allergic reaction:
    • swelling of the face, throat and tongue
    • hives
    • rash
    • breathing problems
  • decreased ability to fight infections. Symptoms of infection may include: fever, pain, aches, chills, feeling tired, nausea and vomiting. Tell your doctor about any signs of infection while you use fluticasone.
  • slow growth in children. The growth of children using fluticasone should be checked regularly.
  • eye problems including glaucoma and cataracts. Tell your doctor about any vision changes while using fluticasone. Your doctor may tell you to have your eyes checked.
  • increased wheezing (bronchospasm). Increased wheezing can happen right away after using fluticasone. Always have a rescue inhaler with you to treat sudden wheezing.
  • lower bone mineral density. This may be a problem for people who already have a higher chance of low bone density (osteoporosis).

Topical:

  • Nasal Spray
    • Fluticasone nasal spray can decrease the activity of your immune system. This will make you more likely to get an infection. Tell your doctor if you are exposed to chickenpox or measles.
    • Corticosteroids, like fluticasone, may slow growth in children. A child taking fluticasone nasal spray should have his/her growth checked regularly.
    • Fluticasone can cause or worsen certain eye conditions including glaucoma and cataracts. Be sure to have regular eye exams while you are taking this medication.
    • Corticosteroids can slow the healing of wounds. Do not use fluticasone nasal spray until your nose has healed if you have a sore in your nose, if you have surgery on your nose, or if your nose has been injured.
    • Hypersensitivity reaction:  An allergic reaction to fluticasone nasal spray can occur.  Tell your doctor if you experience any of the following symptoms of an allergic reaction:
      • difficulty breathing or swallowing
      • hives or rash
      • swelling
      • hoarseness

Fluticasone nasal spray can cause dizziness. Do not drive or operate machinery until you know how fluticasone nasal spray affects you.

To avoid withdrawal side effects, do not stop taking fluticasone nasal spray at once. Discuss with your doctor about slowly decreasing the dose before stopping use of this medication altogether.

Do not take fluticasone nasal spray if you:

  • are allergic to fluticasone nasal spray or any of its ingredients
  • are taking ritonavir (Norvir).
  • Lotion, ointment, or cream
    • decreased adrenal function (adrenal insufficiency). Symptoms of decreased adrenal function include tiredness, weakness, nausea and vomiting, and low blood pressure. Decreased adrenal function can lead to death.

Side effects

Inhalational:

  • Common side effects of fluticasone inhalational include
    • upper airway infection or inflammation
    • throat irritation
    • sinus infection
    • hoarse voice
    • candidiasis
    • cough
    • headache

Topical:

  • Common side effects of fluticasone nasal spray include
    • headache
    • nosebleeds
    • irritated or burning nose
    • runny nose
    • cough
    • nausea
    • stomach pain
    • vomiting
    • diarrhea
    • dizziness
  • Common side effects of fluticasone lotion, ointment, and cream include
    • itching
    • burning
    • increased redness
    • hives
    • irritation
    • lightheadedness
    • an abnormal amount of hair growth over the body (hypertrichosis)

This is not a complete list of fluticasone side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Drug interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • medications that block a protein in the body (CYPA4) such as some macrolide antibiotics (clarithromycin, telithromycin), some HIV protease inhibitors (indinavir, nelfinavir, ritonavir, saquinavir), some HCV protease inhibitors (boceprevir, telaprevir), some azole antifungals (ketoconazole, itraconazole, posaconazole, voriconazole), conivaptan (Vaprisol), delavirdine (Rescriptor), and nefazodone (Serzone)

This is not a complete list of fluticasone drug interactions. Ask your doctor or pharmacist for more information.

Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Fluticasone falls into category C. Studies in animals have shown a harmful and undesired effect on the unborn baby, yet there are no adequate and well-controlled studies in pregnant women.

This medication may be given to a pregnant woman if her healthcare provider believes that its benefits to the pregnant woman outweigh any possible risks to her unborn baby.

Breastfeeding

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if fluticasone is excreted in human breast milk or if it will harm your nursing baby.

Quick facts

Avoid contact with eyes.

It may take 1 to 2 weeks or longer after you start fluticasone Diskus and fluticasone HFA, for your asthma symptoms to get better. You must use fluticasone Diskus and fluticasone HFA regularly. Do not stop using your medication, even if you are feeling better, unless your doctor tells you to.

To avoid withdrawal side effects, do not stop taking fluticasone nasal spray at once. Discuss with your doctor about slowly decreasing the dose before stopping use of this medication altogether.

All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.