Aricept ODT
Generic name: donepezil
Pharmacist-reviewed drug information from the RxWiki encyclopedia.
Overview
Aricept ODT is a prescription medication used to treat Alzheimer's disease. Aricept ODT belongs to a group of drugs called cholinesterase inhibitors. This medication works by stopping a specific enzyme from breaking down acetylcholine in the brain. Acetylcholine is important in many brain functions, including memory, attention, reason, and language.
Aricept ODT comes in an orally disintegrating tablet (ODT). It is usually taken by mouth once a day at bedtime, with or without food. Allow Aricept ODT to dissolve on the tongue and follow with water. Common side effects of Aricept ODT include nausea, diarrhea, and difficulty sleeping.What is it used for?
Aricept ODT is a prescription medicine to treat mild to moderate as well as moderate to severe Alzheimer's disease. Aricept ODT can help with mental function and with doing daily tasks.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.How to take it
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor.
- In mild to moderate Alzheimer's Disease the dosages of Aricept ODT (donepezil) shown to be effective are 5 mg and 10 mg taken by mouth once a day.
- For moderate to severe Alzheimer’s Disease Aricept ODT (donepezil) has been shown to be effective at doses of 10 mg taken by mouth once daily.
Warnings
Aricept ODT may cause the following serious side effects:
- slow heartbeat and fainting. This happens more often in people with heart problems. Call the doctor right away if the patient faints while taking Aricept ODT.
- more stomach acid. This raises the chance of ulcers and bleeding.
- worsening of lung problems in people with asthma or other lung disease.
- seizures.
- difficulty passing urine.
Call the doctor right away if the patient has:
- fainting.
- heartburn or stomach pain that is new or won't go away.
- nausea or vomiting, blood in the vomit, dark vomit that looks like coffee grounds.
- bowel movements or stools that look like black tar.
- new or worse asthma or breathing problems.
- seizures.
- difficulty passing urine.
Do not take Aricept ODT if you are allergic to any of the ingredients in Aricept ODT or to medicines that contain piperidines.
Aricept ODT can cause dizziness, drowsiness, and blurred vision. Do not drive or operate heavy machinery until you know how Aricept ODT affects you.
Side effects
Aricept ODT may cause serious side effects. See "Drug Precautions" section.
The most common side effects of Aricept ODT are:
- nausea
- diarrhea
- not sleeping well
- vomiting
- muscle cramps
- feeling tired
- not wanting to eat
These side effects may get better after the patient takes Aricept ODT for a while. This is not a complete list of side effects with Aricept ODT. For more information, ask the doctor or pharmacist.
Drug interactions
Tell your doctor about all of the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you are taking:
- aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) or naproxen (Aleve). If you take NSAIDs together with Aricept ODT it may make it more likely you will develop stomach ulcers.
- drugs such as phenytoin, carbamazepine, dexamethasone, rifampin, and phenobarbital could decrease the effectiveness of Aricept ODT.
- ipratropium bromide (Atrovent), oxitropium bromide (Oxivent), tiotropium (Spiriva), and Glycopyrrolate (Robinul) may be less effective if taken with dAricept ODT
- Aricept ODT may increase the effectiveness of bethanecol
Because Aricept ODT may cause side effects when taken with certain medicines used for anesthesia, tell your doctor or dentist that you are taking Aricept ODT if you:
- will have surgery or medical procedures
- will have dental surgery or procedures
Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
Aricept ODT falls into category C. There are no adequate or well-controlled studies in pregnant women. It is not known if Aricept ODT can be used in pregnancy or if it will harm an unborn baby. Aricept ODT should be used during pregnancy only if the potential benefit justifies the potential risk to the unborn child.
Breastfeeding
It is not known whether Aricept ODT is excreted into human breast milk or if it will harm a nursing child.
Quick facts
Side effects seen with donepezil may get better after the patient takes donepezil for a while.
Donepezil may cause difficulty passing urine. Call the doctor right away if the patient has difficulty passing urine.
Donepezil can cause a loss in appetite.
All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.