Antihemophilic Factor (Recombinant)

Antihemophilic Factor (Recombinant) is a prescription medication used to prevent, treat, and control bleeding episodes in children and adults with hemophilia A. 

Antihemophilic Factor (Recombinant) belongs to a group of drugs called clotting factors. It works by replacing a protein in the blood that is needed to control bleeding that people with hemophilia A are missing.

This medication comes as a dry powder to be mixed into a solution and injected into a vein (IV). 

Common side effects include fever and headache. 

Antihemophilic Factor (Recombinant) is a prescription medication used to prevent, treat, and control bleeding in adults and children with hemophilia A. This medication may also be used to prevent bleeding during surgery.

This medication is not used to treat von Willebrand Disease.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

The dose and duration of treatment your doctor recommends will be based on the following:

• your weight
• your age
• the severity of factor VIII deficiency
• the location of the bleeding
• your overall clinical condition
• how you respond to this medication

Serious side effects have been reported with this medication including the following:

Hypersensitivity Reactions. Antihemophilic Factor (Recombinant) can cause serious allergic reactions. Tell your healthcare provider immediately about any signs or symptoms of an allergic reaction, which include the following:

• dizziness
• numbness or tingling
• rash
• flushing
• swelling in the face
• hives
• itching
• trouble breathing
• vomiting

Neutralizing antibodies. Your body may form inhibitors to factor VIII, known as antibodies. Antibodies are proteins made by the body as a natural part of the immune system in response to something it recognizes as foreign. If your form these inhibitors, this medication may not work properly. Your healthcare provider will monitor you for development of these inhibitors with blood tests.

Do not receive this medication if you:

• are allergic to antihemophilic factor (recombinant)  or to any of its ingredients
• are allergic to mice or hamsters

Serious side effects have been reported with this medication. See the "Drug Precautions" section.

Common side effects include the following:

• fever
• headache
• cough
• joint pain
• sore throat
• stomach pain
• diarrhea
• chills
• runny nose or congestion
• nausea or vomiting
• itching
• sweating
• swelling of legs
• hot flashes

This is not a complete list of side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

No drug interactions have been reported by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Tell your doctor if you are pregnant or plan to become pregnant.

No studies have been done in animals, and no well-controlled studies have been done in pregnant women. This medication should be given to a pregnant woman only if clearly needed.

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if this medication crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using this medication.