Adynovate

Adynovate is a prescription medication used to control and reduce the number of bleeding episodes in patients with hemophilia A.

Adynovate belongs to a group of drugs called clotting factor replacement treatments. These work by replacing clotting factor that is missing in people with hemophilia.

This medication comes as a dry powder to be mixed into a solution and injected into a vein (IV) by a healthcare provider. Many people with hemophilia A learn to infuse their Adynovate by themselves or with the help of a family member.

Common side effects of Adynovate include headache and nausea.

Adynovate is an injectable prescription medicine used to replace clotting factor (factor VIII or antihemophilic factor) that is missing in adults and children with hemophilia A (also called “classic” hemophilia). Hemophilia A is an inherited bleeding disorder that prevents blood from clotting normally.

• Adynovate is used on-demand to control bleeding in patients with hemophilia A.
• Adynovate may be given to those undergoing surgery.
• Adynovate can reduce the number of bleeding episodes when used regularly (prophylaxis). 

Adynovate is not used to treat von Willebrand disease. 

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

• the condition being treated
• other medical conditions you have
• other medications you are taking
• how you respond to this medication
• your weight
• your height
• your age

Your healthcare provider will tell you how much Adynovate to use based on your weight, level of physical activity, the severity of your hemophilia A, and where you are bleeding.

You should not use Adynovate if you:

• are allergic to mice or hamster protein 
• are allergic to any ingredients in Adynovate or Advate 

Tell your healthcare provider if you are pregnant or breastfeeding because Adynovate may not be right for you.

Common side effects of Adynovate include headache and nausea.

This is not a complete list of Adynovate side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

No drug interactions have been studied by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Tell your doctor if you are pregnant or plan to become pregnant.

There are no studies that have been done in humans or animals with Adynovate. It is not known if Adynovate can harm an unborn baby. Adynovate should only be used in pregnant women if it is clearly needed.

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Adynovate crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Adynovate.