Condition

Syphilis

Syphilis is a sexually transmitted disease (STD) caused by bacteria.

Sexual & reproductive health

Overview

Syphilis is a sexually transmitted disease (STD) caused by bacteria. It infects the genital area, lips, mouth, or anus of both men and women. You usually get syphilis from sexual contact with someone who has it. It can, however, be passed from mother to baby during pregnancy.

Syphilis can be cured with antibiotics if caught early. Although rare, syphilis can cause serious health problems and death as untreated syphilis infection can spread to involve other parts of the body, such as the heart and brain.

Symptoms

  • The early stage of syphilis, known as the primary stage, causes a small, painless sore, usually on the genitals. This sore usually appears about 3 weeks after infection, but may occur up to 90 days after infection. Sores can also be found on anus, in the rectum, or on the lips and in the mouth. Sometimes there may be more than one sore in the primary stage and there may also be swelling in nearby lymph nodes. 
  • Most people with secondary syphilis have a skin rash. The rash, which doesn't itch, is usually on the palms of your hands and soles of your feet. However, it may cover your whole body or appear only in a few areas. The rash appears 2 to 10 weeks after the sore, generally when the sore is healing or already healed.
  • Other symptoms include headache, sore throat, fatigue and swollen lymph nodes. Less commonly seen symptoms include fever, aches, weight loss, hair loss, aching joints, or lesions (sores) in the mouth or genital area.
  • In early latent (hidden) syphilis, signs and symptoms of syphilis may disappear, but the infection remains in your body. When you are in this stage, infecting sexual partners is still possible.
  • Even without treatment, only a small number of infected people develop the dreaded complications known as tertiary, or late, syphilis. In this stage, the bacteria will damage your heart, eyes, brain, nervous system, bones, joints, or almost any other part of your body. This damage can happen years or even decades after the primary stage.
  • Late syphilis can result in mental illness, blindness, deafness, memory loss or other neurologic problems, heart disease, and death. Late neurosyphilis (brain or spinal cord damage) is one of the most severe signs of this stage.
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Causes & risk factors

Syphilis is caused by a bacterium called Treponema pallidum.

The most common way to get syphilis is by having sexual contact with an infected person. If you are infected, you can pass the bacteria from infected skin or mucous membranes (linings), usually your genital area, lips, mouth, or anus, to the mucous membranes or skin of your sexual partner.

The bacteria are fragile, so you cannot get syphilis from sharing food or utensils, or from using tubs, pools, or toilets.

Syphilis can be passed from mother to infant during pregnancy, causing a disease called congenital syphilis.

When to get help

See your doctor for a painless sore, a rash on the palms or soles, or if a partner has syphilis, and get tested, since it can be silent for years. Syphilis is curable with antibiotics, and early treatment prevents serious complications.

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All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.